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1

Crystal structures of pheasant and guinea fowl egg-white lysozymes

Julien Lescar, Hélene Souchon, Pedro M. Alzari

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 6.91 MB

english, 1994

2

Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase

Schulze, Jörg O., Saladino, Giorgio, Busschots, Katrien, Neimanis, Sonja, Süß, Evelyn, Odadzic, Dalibor, Zeuzem, Stefan, Hindie, Valerie, Herbrand, Amanda K., Lisa, María-Natalia, Alzari, Pedro M., Ge

Journal:

Cell Chemical Biology

Year:

2016

Language:

english

File:

PDF, 2.86 MB

english, 2016

3

Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases

Rosario Durán, Andrea Villarino, Marco Bellinzoni, Annemarie Wehenkel, Pablo Fernandez, Brigitte Boitel, Stewart T. Cole, Pedro M. Alzari, Carlos Cerveñansky

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 779 KB

english, 2005

4

Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis

Lisa, María-Natalia, Gil, Magdalena, André-Leroux, Gwénaëlle, Barilone, Nathalie, Durán, Rosario, Biondi, Ricardo M., Alzari, Pedro M.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.33 MB

english, 2015

5

Conformational plasticity of the response regulator CpxR, a key player in Gammaproteobacteria virulence and drug-resistance

Mechaly, Ariel E., Haouz, Ahmed, Sassoon, Nathalie, Buschiazzo, Alejandro, Betton, Jean-Michel, Alzari, Pedro M.

Journal:

Journal of Structural Biology

Year:

2018

Language:

english

File:

PDF, 1.85 MB

english, 2018

6

The crystal structure of Trypanosoma cruzi arginine kinase

Pablo Fernandez, Ahmed Haouz, Claudio A. Pereira, Carlos Aguilar, Pedro M. Alzari

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 193 KB

english, 2007

7

Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase

João Neres, Pascal Bonnet, Philip N. Edwards, Pravin L. Kotian, Alejandro Buschiazzo, Pedro M. Alzari, Richard A. Bryce, Kenneth T. Douglas

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 697 KB

english, 2007

8

Regulation of glutamate metabolism by protein kinases in mycobacteria

Helen M. O'Hare, Rosario Durán, Carlos Cerveñansky, Marco Bellinzoni, Anne Marie Wehenkel, Otto Pritsch, Gonzalo Obal, Jens Baumgartner, Jérome Vialaret, Kai Johnsson, Pedro M. Alzari

Journal:

Molecular Microbiology

Year:

2008

Language:

english

File:

PDF, 492 KB

english, 2008

9

Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives − a screening based on affinity for the UMP-CMP binding site

Dimitri Topalis, Hiroki Kumamoto, Maria-Fernanda Amaya Velasco, Laurence Dugué, Ahmed Haouz, Julie Anne C. Alexandre, Sarah Gallois-Montbrun, Pedro Maria Alzari, Sylvie Pochet, Luigi André Agrofoglio

Journal:

Year:

2007

Language:

english

File:

PDF, 401 KB

english, 2007

10

A common protein fold and similar active site in two distinct families of β-glycanases

Dominguez, Roberto, Souchon, Hélène, Spinelli, Silvia, Dauter, Zbigniew, Wilson, Keith S., Chauvaux, Sylvie, Béguin, Pierre, Alzari, Pedro M.

Journal:

Natural Structural Biology

Year:

1995

File:

PDF, 1.16 MB

1995

11

The crystal structure of a type I cohesin domain at 1.7 Å resolution

Gisele A Tavares, Pierre Béguin, Pedro M Alzari

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 1022 KB

english, 1997

12

Functional in vitro assembly of the integral membrane bacterial thermosensor DesK

Mariana Martín, Daniela Albanesi, Pedro M. Alzari, Diego de Mendoza

Journal:

Protein Expression and Purification

Year:

2009

Language:

english

File:

PDF, 519 KB

english, 2009

13

Plasmodium falciparum Subtilisin-Like Protease 2, a Merozoite Candidate for the Merozoite Surface Protein 1-42 Maturase

Jean-Christophe Barale, Thierry Blisnick, Hisashi Fujioka, Pedro M. Alzari, Masamishi Aikawa, Catherine Braun-Breton and Gordon Langsley

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.40 MB

english, 1999

14

Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c

Bellinzoni, Marco, Haouz, Ahmed, Miras, Isabelle, Magnet, Sophie, André-Leroux, Gwénaëlle, Mukherjee, Raju, Shepard, William, Cole, Stewart T., Alzari, Pedro M.

Journal:

Journal of Structural Biology

Year:

2014

Language:

english

File:

PDF, 1.71 MB

english, 2014

15

Molecular Cloning of a Monoclonal Anti-Tumor Antibody Specific for the Tn Antigen and Expression of an Active Single-Chain Fv Fragment

BABINO, ALVARO, PRITSCH, OTTO, OPPEZZO, PABLO, Du PASQUIER, RENAUD, ROSETO, ALBERTO, OSINAGA, EDUARDO, ALZARI, PEDRO M.

Journal:

Year:

1997

Language:

english

File:

PDF, 2.97 MB

english, 1997

16

Molecular basis of membrane association by the phosphatidylinositol mannosyltransferase PimA from mycobacteria

Rodrigo-Unzueta, Ane, Martínez, Mariano A., Comino, Natalia, Alzari, Pedro M., Chenal, Alexandre, Guerin, Marcelo E.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.34 MB

english, 2016

17

Continuous fluorimetric assay for high-throughput screening of inhibitors of trans-sialidase from Trypanosoma cruzi

João Neres, Alejandro Buschiazzo, Pedro M. Alzari, Lindsey Walsh, Kenneth T. Douglas

Journal:

Analytical Biochemistry

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

18

Crystallization and preliminary X-ray diffraction study of an endoglucanase from Clostridium thermocellum

Gwennaël Joliff, Pierre Béguin, Jacqueline Millet, Jean-Paul Aubert, Pedro Alzari, Michel Juy, Roberto J. Poljak

Journal:

Journal of Molecular Biology

Year:

1986

Language:

english

File:

PDF, 145 KB

english, 1986

19

Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis

East, Alexandra, Mechaly, Ariel E., Huysmans, Gerard H.M., Bernarde, Cédric, Tello-Manigne, Diana, Nadeau, Nathalie, Pugsley, Anthony P., Buschiazzo, Alejandro, Alzari, Pedro M., Bond, Peter J., Franc

Journal:

Year:

2015

Language:

english

File:

PDF, 5.51 MB

english, 2015

20

Unexpected electron spin density on the axial methionine ligand in Cu A suggests its involvement in electron pathways

Morgada, Marcos N., Llases, María-Eugenia, Giannini, Estefanía, Castro, María-Ana, Alzari, Pedro M., Murgida, Daniel H., Lisa, María-Natalia, Vila, Alejandro J.

Journal:

Chemical Communications

Year:

2020

Language:

english

File:

PDF, 1.20 MB

english, 2020

21

Subcloning of a dna fragment encoding a single cohesin domain of the clostridium thermocellum cellulosome-integrating protein cipA: Purification, crystallization, and preliminary diffraction analysis of the encoded polypeptide

Pierre Béguin, Odette Raynaud, Marie-Kim Chaveroche, Abel Dridi, Pedro M. Alzari

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 2.06 MB

english, 1996

22

Crystallization and Preliminary Crystallographic Analysis of a Tetrameric Isolectin from Vicia villosa, Specific for the Tn Antigen

Jean-Luc Eiselé, Diana Tello, Eduardo Osinaga, Alberto Roseto, Pedro M. Alzari

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 134 KB

1993

23

Bacterial Metabolism under FHA Control

Marco Bellinzoni, Pedro M. Alzari

Journal:

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

24

Substrate-Selective Inhibition of Protein Kinase PDK1 by Small Compounds that Bind to the PIF-Pocket Allosteric Docking Site

Katrien Busschots, Laura A. Lopez-Garcia, Carmen Lammi, Adriana Stroba, Stefan Zeuzem, Albrecht Piiper, Pedro M. Alzari, Sonja Neimanis, Jose M. Arencibia, Matthias Engel, Jörg O. Schulze, Ricardo M.

Journal:

Chemistry & Biology

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

25

Structure and Mechanism of the Alkyl Hydroperoxidase AhpC, a Key Element of the Mycobacterium tuberculosis Defense System against Oxidative Stress

Guimarães, Beatriz G., Souchon, Hélène, Honoré, Nadine, Saint-Joanis, Brigitte, Brosch, Roland, Shepard, William, Cole, Stewart T., Alzari, Pedro M.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 1.06 MB

english, 2005

26

Structural insights into sialic acid enzymology

Alejandro Buschiazzo, Pedro M Alzari

Journal:

Current Opinion in Chemical Biology

Year:

2008

Language:

english

File:

PDF, 704 KB

english, 2008

27

The carboxy-terminal C2-like domain of the α-toxin from Clostridium perfringens mediates calcium-dependent membrane recognition

Isabelle Guillouard, Pedro M. Alzari, Bernard Saliou, Stewart T. Cole

Journal:

Molecular Microbiology

Year:

1997

Language:

english

File:

PDF, 1.25 MB

english, 1997

28

Three-dimensional structure of a thermostable bacterial cellulase

Juy, Michel, Amrt, Adolfo G., Alzari, Pedro M., Poljak, Roberta J., Claeyssens, Marc, Béguin, Pierre, Aubert, Jean-Paul

Journal:

Year:

1992

File:

PDF, 457 KB

1992

29

The Crystal Structure and Mode of Action of Trans-Sialidase, a Key Enzyme in Trypanosoma cruzi Pathogenesis

Alejandro Buschiazzo, Marı́a F. Amaya, Marı́a L. Cremona, Alberto C. Frasch, Pedro M. Alzari

Journal:

Year:

2002

Language:

english

File:

PDF, 539 KB

english, 2002

30

Preliminary crystallographic study of a complex between an heteroclitic anti-hen egg-white lysozyme antibody and the heterologous antigen pheasant egg-white lysozyme

Guillon, Véronique, Alzari, Pedro M., Poljak, Roberto J.

Journal:

Journal of Molecular Biology

Year:

1987

Language:

english

File:

PDF, 191 KB

english, 1987

31

Arabidopsis thaliana Hcc1 is a Sco‐like metallochaperone for Cu A assembly in Cytochrome c Oxidase

Llases, María‐Eugenia, Lisa, María‐Natalia, Morgada, Marcos N., Giannini, Estefanía, Alzari, Pedro M., Vila, Alejandro J.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.56 MB

english, 2019

32

High-Throughput Crystallization Pipeline at the Crystallography Core Facility of the Institut Pasteur

Weber, Patrick, Pissis, Cédric, Navaza, Rafael, Mechaly, Ariel E., Saul, Frederick, Alzari, Pedro M., Haouz, Ahmed

Journal:

Year:

2019

File:

PDF, 1.25 MB

2019

33

The crystal structure of endoglucanase CelA, a family 8 glycosyl hydrolase from Clostridium thermocellum

Pedro M Alzari, Hélè ne Souchon, Roberto Dominguez

Journal:

Year:

1996

Language:

english

File:

PDF, 1.56 MB

english, 1996

34

The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation

Wagner, Tristan, Alexandre, Matthieu, Duran, Rosario, Barilone, Nathalie, Wehenkel, Annemarie, Alzari, Pedro M., Bellinzoni, Marco

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

35

Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation

Mechaly, Ariel E., Sassoon, Nathalie, Betton, Jean-Michel, Alzari, Pedro M., Hughson, Frederick

Journal:

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

36

Modification in hydrophobic packing of HAMP domain induces a destabilization of the auto-phosphorylation site in the histidine kinase CpxA

Martinez, Marlet, Duclert-Savatier, Nathalie, Betton, Jean-Michel, Alzari, Pedro M, Nilges, Michael, Malliavin, Thérèse E

Journal:

Year:

2016

Language:

english

File:

PDF, 7.57 MB

english, 2016

37

Novel mechanistic insights into physiological signaling pathways mediated by mycobacterial Ser/Thr protein kinases

Bellinzoni, Marco, Wehenkel, Anne Marie, Durán, Rosario, Alzari, Pedro M.

Journal:

Genes and Immunity

Year:

2019

Language:

english

File:

PDF, 1.70 MB

english, 2019

38

Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts

Wagner, Tristan, Boyko, Alexandra, Alzari, Pedro M., Bunik, Victoria I., Bellinzoni, Marco

Journal:

Journal of Structural Biology

Year:

2019

Language:

english

File:

PDF, 1.87 MB

english, 2019

39

Functional Plasticity and Allosteric Regulation of α-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism

Tristan Wagner, Marco Bellinzoni, Annemarie Wehenkel, Helen M. O'Hare, Pedro M. Alzari

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

40

Sub-families of α/β Barrel Enzymes: A New Adenine Deaminase Family

Carin Ribard, Michel Rochet, Bernard Labedan, Bertrand Daignan-Fornier, Pedro Alzari, Claudio Scazzocchio, Nathalie Oestreicher

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.94 MB

english, 2003

41

The Crystal Structure and Catalytic Mechanism of Cellobiohydrolase CelS, the Major Enzymatic Component of the Clostridium thermocellum Cellulosome

Beatriz G. Guimarães, Hélène Souchon, Betsy L. Lytle, J.H. David Wu, Pedro M. Alzari

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 1.60 MB

english, 2002

42

Three-Dimensional Structure of Rat Liver 3α-Hydroxysteroid/ Dihydrodiol Dehydrogenase: A Member of the Aldo-Keto Reductase Superfamily

Susan S. Hoog, John E. Pawlowski, Pedro M. Alzari, Trevor M. Penning and Mitchell Lewis

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.24 MB

english, 1994

43

Resolution of Hypervariable Regions in T-Cell Receptor β Chains by a Modified Wu-Kabat Index of Amino Acid Diversity

Rita Jores, Pedro M. Alzari and Tommaso Meo

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.01 MB

english, 1990

44

Poly(Glu60Ala30Tyr10) (GAT)-induced IgG monoclonal antibodies cross-react with various self and non-self antigens through the complementarity determining regions. Comparison with IgM monoclonal polyreactive natural antibodies

Rosana González-Quintial, Roberto Baccalá, Pedro Maria Alzari, Clara Nahmias, Gilbert Mazza, Michel Fougereau, Stratis Avrameas

Journal:

European Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 491 KB

english, 1990

45

Biochemical and functional characterization of the Tn-specific lectin from Salvia sclarea seeds

Andrea Medeiros, Sergio Bianchi, Juan J. Calvete, Henia Balter, Sylvie Bay, Ana Robles, Danièle Cantacuzène, Manfred Nimtz, Pedro M. Alzari, Eduardo Osinaga

Journal:

Year:

2000

Language:

english

File:

PDF, 566 KB

english, 2000

46

First Structural Glimpse at a Bacterial Ser/Thr Protein Phosphatase

Pedro M. Alzari

Journal:

Year:

2004

Language:

english

File:

PDF, 37 KB

english, 2004

47

Mechanisms determining cell membrane expression of different γδ TCR chain pairings

Laurent Boucontet, Martin Grana, Pedro M. Alzari, Pablo Pereira

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 353 KB

english, 2009

48

The Crystal Structure of a Family 5 Endoglucanase Mutant in Complexed and Uncomplexed Forms Reveals an Induced Fit Activation Mechanism

Roberto Domı́nguez, Hélène Souchon, Marie-Bernard Lascombe, Pedro M. Alzari

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 591 KB

english, 1996

49

Structural Features Involved in the Formation of a Complex between the Monomeric or the Dimeric Form of the Rev-erbβ DNA-Binding Domain and Its DNA Reactive Sites †,‡

Terenzi, Hernan, Alzari, Pedro M., Zakin, Mario M.

Journal:

Year:

1998

Language:

english

File:

PDF, 186 KB

english, 1998

50

Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis

Beate Heym, Pedro M. Alzari, Nadine Honore, Stewart T. Cole

Journal:

Molecular Microbiology

Year:

1995

Language:

english

File:

PDF, 5.55 MB

english, 1995

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